The natural sciences are an accepted part of the setting, blending with magic to create a greater whole. As knowledge is gained, a combination of observation and experiment is merged with divination and sorcery to grant greater insights into the way the world works. Magic and science are not enemies, but feed off of one another, allowing a much more rapid degree of progress. Three nations have taken the lead in the study of science and magic – Tarantis uses magic to augment the study of science while R’Tal uses science to augment the study of magic. Anansie uses mathematics and art, blending the two into wonders.

Science is capable of incredible feats, and artificing is a respected pursuit. Airships drift over the city of Siren's Cove, while the city of Anansie has clockwork wonders walking through the streets, following behind the rich. In R’Tal, science allows the curious to peer through the void and into the spirit world, or allows one to talk to the dead. The ships of Tarantis hold cannons while the soldiers use long arms as a powerful first strike in combat.